I created a ManageWP account to help with automating WordPress updates but also noticed that it will help with optimization of WordPress.  I did some research into the optimization options.

  • Spam
    • This commands deletes comments that have been marked as spam.  
  • Post Revisions
    • When you save updates to posts, WordPress saves a copy if you want to revert.  So, from time to time this is good to cleanup.  ManageWP saves the last 5 revisions though you can alter that value.
  • Database Performance
    • This will optimize the database. 

ManageWP also have an Optimize All command.